대한흉부영상의학회 Weekly Chest Cases

Courtesy of Yoon Kyung Kim, M.D., Kyung Soo Lee, M.D. / Samsung Medical Center, Sungkyunkwan University, Seoul, Korea
Age/Sex 23 / M
Chief ComplaintCough, dyspnea

Diagnosis: Adenovirus Pneumonia with Acute Lung Injury
Radiologic Findings: Chest radiograph shows diffuse ground-glass opacities in both lungs. High resolution CT scan obtained at level of carina and inferior pulmonary vein show ground-glass opacities in both lungs.
Brief Review: In adults, adenovirus pneumonia occurs commonly in immunocompromised hosts including patients who have received organ and bone marrow transplants, whereas in healthy individuals it is rare. Adenovirus pneumonia presented with patchy ground-glass opacities with or without consolidation on HRCT in both immunocompromised and immunocompetent patients. Ground-glass opacity corresponds histopathologically to areas of acute diffuse alveolar damage comprising interstitial lymphocyte infiltration, intraalveolar hemorrhage, edema and fibrin, type II cell hyperplasia, and hyaline membrane formation. Alveolar lining cells show intranuclear inclusions, which is positive for immunohistochemical staining.
References: Chong S, Lee KS, Kim TS, et al. Adenovirus pneumonia in adults: radiographic and high-resolution CT findings in five patients. AJR 2006; 186:1288-1293.
Keywords: Lung, Infection, Viral infection// Permeability edema,

대한흉부영상의학회 Korean Society of Thoracic Radiology